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NMN is an entirely natural compound found in our bodies. Various food sources also contain this compound in minus-cule amounts. Edamame which has one of the higher contents, only show less than 1.9mg1100g. NMN is a direct and potent NAD+ supplement. Mice given an oral supple-ment of NMN showed increased liver NAD+ levels in just 10 minutes and showed an increase in muscle tissue by 30 minutes. Increased NAD+ levels stimulate energy DNA repair and SIRTUIN activity. SIRTUINS are the longevi¬ty-genes shown to be active during caloric restriction and life-extension in many animal models.

Research of NMN and NAD+

Scientists have now confirmed a direct link between falling NAD+ levels and aging in both animals and human subjects. A breakthrough study published by Harvard scientists in 2013 showed for the first time that some aspects of aging might be reversible. After treating old mice with NMN, several biometric markers that were subsequent¬ly measured resembled those of young mice: "the human equivalent of a 60-year old with markers resembling that of a 20-year old". The research and understanding into NAD+ metabolomics are ongoing, but what the science has highlighted thus far, is the importance of supporting and maintaining our NAD+ levels.

A long-term evaluation of oral supplementation of NMN in mice was found to be effective at improving NAD+ levels safely. Mice supplemented with NMN vs. a control group showed notable age-associated differences in mass, energy, blood sugar, lipid, gene expression changes, mitochondrial oxygen use, eye function, bone density and immune function with no apparent toxic effects.


NMN 9000

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